Differential niche and Wnt requirements during acute myeloid leukemia progression

Hematopoietic stem cells (HSCs) engage in complex bidirectional signals with the hematopoietic microenvironment (HM), and there is emerging evidence that leukemia stem cells (LSCs) may use similar interactions. Using a syngeneic retroviral model of MLL-AF9 induced acute myeloid leukemia (AML), we ha...

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Detalhes bibliográficos
Main Authors: Lane, Steven W., Wang, Yingzi J., Lo Celso, Cristina, Ragu, Christine, Bullinger, Lars, Sykes, Stephen M., Ferraro, Francesca, Shterental, Sebastian, Lin, Charles P., Gilliland, D. Gary, Scadden, David T., Armstrong, Scott A., Williams, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172801/
https://ncbi.nlm.nih.gov/pubmed/21765021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-345165
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