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Targeting adhesion to the vascular niche to improve therapy for acute myeloid leukemia

Niche hijack by malignant cells is considered to be a prominent cause of disease relapse. Barbier and colleagues uncover (E)-selectin as a novel mediator of malignant cell survival and regeneration which, upon blockade, has the potential to significantly improve therapeutic outcomes.

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Detalles Bibliográficos
Publicado en:Nat Commun
Autores principales: Haltalli, Myriam L. R., Lo Celso, Cristina
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378234/
https://ncbi.nlm.nih.gov/pubmed/32703951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17594-7
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