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NMDA Receptor Blockade at Rest Triggers Rapid Behavioural Antidepressant Responses
Clinical studies consistently demonstrate that a single sub-psychomimetic dose of ketamine, an ionotropic glutamatergic n-methyl-d-aspartate receptor (NMDAR) antagonist, produces fast-acting antidepressant responses in patients suffering from major depressive disorder (MDD), although the underlying...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172695/ https://ncbi.nlm.nih.gov/pubmed/21677641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10130 |
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