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Age dependence of the rapid antidepressant and synaptic effects of acute NMDA receptor blockade
Ketamine is a N-methyl-D-aspartate receptor (NMDAR) antagonist that produces rapid antidepressant responses in individuals with major depressive disorder. The antidepressant action of ketamine has been linked to blocking NMDAR activation at rest, which inhibits eukaryotic elongation factor 2 kinase...
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| Publicado no: | Front Mol Neurosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4249453/ https://ncbi.nlm.nih.gov/pubmed/25520615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00094 |
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