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Prechemistry Versus Preorganization in DNA Replication Fidelity
The molecular origin of nucleotide insertion catalysis and fidelity of DNA polymerases is explored by means of computational simulations. Special attention is paid to the examination of the validity of proposals that invoke prechemistry effects, checkpoints concepts and dynamical effects. The simula...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172682/ https://ncbi.nlm.nih.gov/pubmed/21905114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23128 |
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