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Misunderstanding the Preorganization Concept can lead to Confusions about the Origin of Enzyme Catalysis

Understanding the origin of the catalytic power of enzymes has both conceptual and practical importance. One of the most important finding from computational studies of enzyme catalysis is that a major part of the catalytic power is due to the preorganization of the enzyme active site. Unfortunately...

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Dettagli Bibliografici
Pubblicato in:Proteins
Autori principali: Jindal, Garima, Warshel, Arieh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760166/
https://ncbi.nlm.nih.gov/pubmed/28905418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25381
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