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Misunderstanding the Preorganization Concept can lead to Confusions about the Origin of Enzyme Catalysis

Understanding the origin of the catalytic power of enzymes has both conceptual and practical importance. One of the most important finding from computational studies of enzyme catalysis is that a major part of the catalytic power is due to the preorganization of the enzyme active site. Unfortunately...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Jindal, Garima, Warshel, Arieh
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760166/
https://ncbi.nlm.nih.gov/pubmed/28905418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25381
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