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A binding free energy decomposition approach for accurate calculations of the fidelity of DNA polymerases
DNA polymerase β (pol β) is a small eukaryotic enzyme with the ability to repair short single-stranded DNA gaps that has found use as a model system for larger replicative DNA polymerases. For all DNA polymerases, the factors determining their catalytic power and fidelity are the interactions betwee...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966340/ https://ncbi.nlm.nih.gov/pubmed/19842163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22596 |
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