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Bcl-2 interaction with the inositol 1,4,5-trisphosphate receptor: role in Ca(2+) signaling and disease

The Bcl-2 protein, best known for its ability to inhibit apoptosis, interacts with the inositol 1,4,5-trisphosphate receptor (IP(3)R) Ca(2+) channel to regulate IP(3)-mediated Ca(2+) release from the endoplasmic reticulum. This review summarizes the current state of knowledge regarding the interacti...

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Détails bibliographiques
Auteurs principaux: Distelhorst, Clark W., Bootman, Martin D.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172391/
https://ncbi.nlm.nih.gov/pubmed/21628070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2011.05.011
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