The role of inositol 1,4,5-trisphosphate receptors in Ca(2+) signalling and the generation of arrhythmias in rat atrial myocytes

Various cardio-active stimuli, including endothelin-1 (ET-1), exhibit potent arrhythmogenicity, but the underlying cellular mechanisms of their actions are largely unclear. We used isolated rat atrial myocytes and related changes in their subcellular Ca(2+) signalling to the ability of various stimu...

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Bibliographic Details
Main Authors: Mackenzie, Lauren, Bootman, Martin D, Laine, Mika, Berridge, Michael J, Thuring, Jan, Holmes, Andrew, Li, Wen-Hong, Lipp, Peter
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2002
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290330/
https://ncbi.nlm.nih.gov/pubmed/12042347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013411
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