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Inhibition of the P2X7 Receptor Reduces Cystogenesis in PKD
The P2X7 receptor participates in purinergic signaling, which may promote the progression of ADPKD. We examined the effects of a P2X7 receptor antagonist and a P2X7 receptor agonist on cyst development in a zebrafish model of polycystic kidney disease in which we knocked down pkd2 by morpholinos. We...
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Main Authors: | , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society of Nephrology
2011
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171940/ https://ncbi.nlm.nih.gov/pubmed/21636640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010070728 |
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