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Effect of Trehalose Supplementation on Autophagy and Cystogenesis in a Mouse Model of Polycystic Kidney Disease

Autophagy impairment has been demonstrated in the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) and could be a new target of treatment. Trehalose is a natural, nonreducing disaccharide that has been shown to enhance autophagy. Therefore, we investigated whether trehalose treat...

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Publicado en:Nutrients
Main Authors: Chou, Li-Fang, Cheng, Ya-Lien, Hsieh, Chun-Yih, Lin, Chan-Yu, Yang, Huang-Yu, Chen, Yung-Chang, Hung, Cheng-Chieh, Tian, Ya-Chung, Yang, Chih-Wei, Chang, Ming-Yang
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356442/
https://ncbi.nlm.nih.gov/pubmed/30585217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11010042
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