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Autophagy activators suppress cystogenesis in an autosomal dominant polycystic kidney disease model
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in either PKD1 or PKD2. It is one of the most common heritable human diseases with eventual development of renal failure; however, effective treatment is lacking. While inhibition of mechanistic target of rapamycin (mTOR) ef...
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| Veröffentlicht in: | Hum Mol Genet |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6251521/ https://ncbi.nlm.nih.gov/pubmed/28007903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw376 |
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