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Smad3-Mediated Upregulation of miR-21 Promotes Renal Fibrosis
TGF-β/Smad signaling plays a role in fibrogenesis, but therapies targeting TGF-β are ineffective in treating renal fibrosis. Here, we explored the therapeutic potential of targeting TGF-β-induced microRNA in the progression of renal fibrosis. Microarray analysis and real-time PCR revealed upregulati...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Nephrology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171938/ https://ncbi.nlm.nih.gov/pubmed/21852586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010111168 |
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