Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites

Abasic (AP) sites arise in DNA through spontaneous base loss and enzymatic removal of damaged bases. APN1 encodes the major AP-endonuclease of Saccharomyces cerevisiae. Human HAP1 (REF1) encodes the major AP endonuclease which, in addition to its role in DNA repair, functions as a redox regulatory p...

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書誌詳細

出版年:	Genes Dev
主要な著者:	Johnson, Robert E., Torres-Ramos, Carlos A., Izumi, Tadahide, Mitra, Sankar, Prakash, Satya, Prakash, Louise
フォーマット:	Artigo
言語:	Inglês
出版事項:	Cold Spring Harbor Laboratory Press 1998
主題:	Research Paper
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317187/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765213/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.19.3137
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