Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites

Abasic (AP) sites arise in DNA through spontaneous base loss and enzymatic removal of damaged bases. APN1 encodes the major AP-endonuclease of Saccharomyces cerevisiae. Human HAP1 (REF1) encodes the major AP endonuclease which, in addition to its role in DNA repair, functions as a redox regulatory p...

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הוצא לאור ב:	Genes Dev
Principais autores:	Johnson, Robert E., Torres-Ramos, Carlos A., Izumi, Tadahide, Mitra, Sankar, Prakash, Satya, Prakash, Louise
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Cold Spring Harbor Laboratory Press 1998
נושאים:	Research Paper
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317187/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765213/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.19.3137
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