Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites

Abasic (AP) sites arise in DNA through spontaneous base loss and enzymatic removal of damaged bases. APN1 encodes the major AP-endonuclease of Saccharomyces cerevisiae. Human HAP1 (REF1) encodes the major AP endonuclease which, in addition to its role in DNA repair, functions as a redox regulatory p...

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Dades bibliogràfiques

Publicat a:	Genes Dev
Autors principals:	Johnson, Robert E., Torres-Ramos, Carlos A., Izumi, Tadahide, Mitra, Sankar, Prakash, Satya, Prakash, Louise
Format:	Artigo
Idioma:	Inglês
Publicat:	Cold Spring Harbor Laboratory Press 1998
Matèries:	Research Paper
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317187/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765213/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.19.3137
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