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eIF2α kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver
In eukaryotes, selective derepression of mRNA translation through altered utilization of upstream open reading frames (uORF) or internal ribosomal entry sites (IRES) regulatory motifs following exposure to stress is regulated at the initiation stage through the increased phosphorylation of eukaryoti...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171828/ https://ncbi.nlm.nih.gov/pubmed/19509078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.90396.2008 |
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