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eIF2α kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver

In eukaryotes, selective derepression of mRNA translation through altered utilization of upstream open reading frames (uORF) or internal ribosomal entry sites (IRES) regulatory motifs following exposure to stress is regulated at the initiation stage through the increased phosphorylation of eukaryoti...

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Detalhes bibliográficos
Main Authors: Dang Do, An N., Kimball, Scot R., Cavener, Douglas R., Jefferson, Leonard S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171828/
https://ncbi.nlm.nih.gov/pubmed/19509078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.90396.2008
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