eIF2α kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver

In eukaryotes, selective derepression of mRNA translation through altered utilization of upstream open reading frames (uORF) or internal ribosomal entry sites (IRES) regulatory motifs following exposure to stress is regulated at the initiation stage through the increased phosphorylation of eukaryoti...

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Main Authors: Dang Do, An N., Kimball, Scot R., Cavener, Douglas R., Jefferson, Leonard S.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171828/
https://ncbi.nlm.nih.gov/pubmed/19509078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.90396.2008
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