Mechanism by Which Mcl-1 Regulates Cancer-Specific Apoptosis Triggered by mda-7/IL-24, an IL-10-Related Cytokine

Melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24), a cytokine belonging to the IL-10 family, selectively induces apoptosis in cancer cells without harming normal cells by promoting an endoplasmic reticulum (ER) stress response. The precise molecular mechanism by which the ER st...

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Detalhes bibliográficos
Main Authors: Dash, Rupesh, Richards, Joanna E., Su, Zhao-zhong, Bhutia, Sujit K., Azab, Belal, Rahmani, Mohamed, Dasmahapatra, Girija, Yacoub, Adly, Dent, Paul, Dmitriev, Igor P., Curiel, David T., Grant, Steven, Pellecchia, Maurizio, Reed, John C., Sarkar, Devanand, Fisher, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171699/
https://ncbi.nlm.nih.gov/pubmed/20501829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0563
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