Autophagy switches to apoptosis in prostate cancer cells infected with melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24)

MDA-7/IL-24 has noteworthy potential as an anticancer therapeutic because of its diversity of antitumor properties, its lack of toxicity toward normal cells and tissues, and its safety and efficacy as evidenced in a phase I clinical trial. In a recent study, we document that Ad.mda-7-induced ER stre...

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Bibliographic Details
Main Authors: Bhutia, Sujit K, Das, Swadesh K, Azab, Belal, Dash, Rupesh, Su, Zhao-zhong, Lee, Seok-Geun, Dent, Paul, Curiel, David T, Sarkar, Devanand, Fisher, Paul B
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
Subjects:
Autophagic Punctum
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210317/
https://ncbi.nlm.nih.gov/pubmed/21610321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.9.16163
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