Autophagy switches to apoptosis in prostate cancer cells infected with melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24)

MDA-7/IL-24 has noteworthy potential as an anticancer therapeutic because of its diversity of antitumor properties, its lack of toxicity toward normal cells and tissues, and its safety and efficacy as evidenced in a phase I clinical trial. In a recent study, we document that Ad.mda-7-induced ER stre...

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Bibliographische Detailangaben
Hauptverfasser: Bhutia, Sujit K, Das, Swadesh K, Azab, Belal, Dash, Rupesh, Su, Zhao-zhong, Lee, Seok-Geun, Dent, Paul, Curiel, David T, Sarkar, Devanand, Fisher, Paul B
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2011
Schlagworte:
Autophagic Punctum
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210317/
https://ncbi.nlm.nih.gov/pubmed/21610321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.9.16163
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