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Insulin-like Growth Factor (IGF)-I and IGF-II Contribute Differentially to the Phenotype of Pregnancy Associated Plasma Protein-A Knock-out Mice

CONTEXT: Insulin-like growth factor (IGF) signaling is essential for achieving optimal body size during fetal development, peak bone mass during puberty, and maximal fecundity in the reproductive period. IGF-II is considered the main fetal IGF, whereas IGF-I is more important postnatally. Pregnancy-...

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Detalhes bibliográficos
Main Authors: Mason, Emily J., Grell, Jacquelyn A., Wan, Junxiang, Cohen, Pinchas, Conover, Cheryl A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171618/
https://ncbi.nlm.nih.gov/pubmed/21802327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2011.06.002
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