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Central insulin‐like growth factor‐1 (IGF‐1) restores whole‐body insulin action in a model of age‐related insulin resistance and IGF‐1 decline

Low insulin‐like growth factor‐1 (IGF‐1) signaling is associated with improved longevity, but is paradoxically linked with several age‐related diseases in humans. Insulin‐like growth factor‐1 has proven to be particularly beneficial to the brain, where it confers protection against features of neuro...

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Detalles Bibliográficos
Publicado en:Aging Cell
Main Authors: Huffman, Derek M., Farias Quipildor, Gabriela, Mao, Kai, Zhang, Xueying, Wan, Junxiang, Apontes, Pasha, Cohen, Pinchas, Barzilai, Nir
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717281/
https://ncbi.nlm.nih.gov/pubmed/26534869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12415
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