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Central insulin‐like growth factor‐1 (IGF‐1) restores whole‐body insulin action in a model of age‐related insulin resistance and IGF‐1 decline

Low insulin‐like growth factor‐1 (IGF‐1) signaling is associated with improved longevity, but is paradoxically linked with several age‐related diseases in humans. Insulin‐like growth factor‐1 has proven to be particularly beneficial to the brain, where it confers protection against features of neuro...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Huffman, Derek M., Farias Quipildor, Gabriela, Mao, Kai, Zhang, Xueying, Wan, Junxiang, Apontes, Pasha, Cohen, Pinchas, Barzilai, Nir
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717281/
https://ncbi.nlm.nih.gov/pubmed/26534869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12415
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