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Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity
Attenuated growth hormone and insulin-like growth factor-1 (GH/IGF-1) signaling is associated with extended lifespan in several animal models. However, the effect of diminished GH/IGF-1 activity on survival in humans has not been confirmed. We tested the hypothesis that IGF-1 levels in nonagenarians...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BlackWell Publishing Ltd
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4116456/ https://ncbi.nlm.nih.gov/pubmed/24618355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12213 |
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