Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice

Disruptions in growth hormone/insulin-like growth factor-1 (GH/IGF-1) signaling have been linked to improved longevity in mice and humans. Nevertheless, while IGF-1 levels are associated with increased cancer risk, they have been paradoxically implicated with protection from other age-related condit...

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Detalhes bibliográficos
Publicado no:GeroScience
Main Authors: Farias Quipildor, Gabriela E., Mao, Kai, Hu, Zunju, Novaj, Ardijana, Cui, Min-Hui, Gulinello, Maria, Branch, Craig A., Gubbi, Sriram, Patel, Khushbu, Moellering, Douglas R., Tarantini, Stefano, Kiss, Tamas, Yabluchanskiy, Andriy, Ungvari, Zoltan, Sonntag, William E., Huffman, Derek M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544744/
https://ncbi.nlm.nih.gov/pubmed/31076997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00065-3
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