Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1–dependent cellular transformation

GSK-3β-dependent phosphorylation of cyclin D1 at Thr-286 promotes the nuclear-to-cytoplasmic redistribution of cyclin D1 during S phase of the cell cycle, but how phosphorylation regulates redistribution has not been resolved. For example, phosphorylation of nuclear cyclin D1 could increase its rate...

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Autores principales: Alt, Jodi R., Cleveland, John L., Hannink, Mark, Diehl, J. Alan
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2000
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC317128/
https://ncbi.nlm.nih.gov/pubmed/11124803
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