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Protein Kinase C-β Gene Variants, Pathway Activation, and Enzastaurin Activity in Lung Cancer
BACKGROUND: Protein kinase C-β2 (PKCβ2) is a splice-variant of the PRKCB1 gene and belongs to a family of serine/threonine-specific kinases that are predominantly activated by diacylglycerol, calcium, and phorbol ester. Cellular functions associated with PKCβ2 activation include transformation, prol...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3171168/ https://ncbi.nlm.nih.gov/pubmed/20439192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3816/CLC.2010.n.021 |
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