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Differential Role of β(1C) and β(1A) Integrin Cytoplasmic Variants in Modulating Focal Adhesion Kinase, Protein Kinase B/AKT, and Ras/Mitogen-activated Protein Kinase Pathways
The integrin cytoplasmic domain modulates cell proliferation, adhesion, migration, and intracellular signaling. The β(1) integrin subunits, β(1C) and β(1A), that contain variant cytoplasmic domains differentially affect cell proliferation; β(1C) inhibits proliferation, whereas β(1A) promotes it. We...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Cell Biology
2000
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC14916/ https://ncbi.nlm.nih.gov/pubmed/10888665 |
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