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α5β1 Integrin Controls Cyclin D1 Expression by Sustaining Mitogen-activated Protein Kinase Activity in Growth Factor-treated Cells

Cyclin D1 expression is jointly regulated by growth factors and cell adhesion to the extracellular matrix in many cell types. Growth factors are thought to regulate cyclin D1 expression because they stimulate sustained extracellular signal-regulated kinase (ERK) activity. However, we show here that...

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Detalhes bibliográficos
Main Authors: Roovers, Kristin, Davey, Gabriela, Zhu, Xiaoyun, Bottazzi, Maria Elena, Assoian, Richard K.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25578/
https://ncbi.nlm.nih.gov/pubmed/10512860
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