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Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells

It has long been hypothesized that abnormalities in lipid biology contribute to degenerative brain diseases. Consistent with this, emerging epidemiologic evidence links lipid alterations with Parkinson disease (PD), and disruption of lipid metabolism has been found to predispose to α-synuclein toxic...

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Detalhes bibliográficos
Main Authors: Kim, Kye-Young, Stevens, Mark V., Akter, M. Hasina, Rusk, Sarah E., Huang, Robert J., Cohen, Alexandra, Noguchi, Audrey, Springer, Danielle, Bocharov, Alexander V., Eggerman, Tomas L., Suen, Der-Fen, Youle, Richard J., Amar, Marcelo, Remaley, Alan T., Sack, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171101/
https://ncbi.nlm.nih.gov/pubmed/21865652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44736
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