Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1 Interacting Genes

Inherited BRCA1 mutations confer elevated breast cancer risk. Recent studies have identified genes that encode proteins that interact with BRCA1 as modifiers of BRCA1-associated breast cancer. We evaluated a comprehensive set of genes that encode most known BRCA1 interactors to evaluate the role of...

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Auteurs principaux: Rebbeck, Timothy R., Mitra, Nandita, Domchek, Susan M., Wan, Fei, Friebel, Tara M., Tran, Teo V., Singer, Christian F., Tea, Muy-Kheng Maria, Blum, Joanne L., Tung, Nadine, Olopade, Olufunmilayo I., Weitzel, Jeffrey N., Lynch, Henry T., Snyder, Carrie L., Garber, Judy E., Antoniou, Antonis C., Peock, Susan, Evans, D. Gareth, Paterson, Joan, Kennedy, M. John, Donaldson, Alan, Dorkins, Huw, Easton, Douglas F., Rubinstein, Wendy S., Daly, Mary B., Isaacs, Claudine, Nevanlinna, Heli, Couch, Fergus J., Andrulis, Irene L., Freidman, Eitan, Laitman, Yael, Ganz, Patricia A., Tomlinson, Gail E., Neuhausen, Susan L., Narod, Steven A., Phelan, Catherine M., Greenberg, Roger, Nathanson, Katherine L.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170727/
https://ncbi.nlm.nih.gov/pubmed/21799032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0773
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