Nuclear organization of DNA replication in primary mammalian cells

Using methods that conserve nuclear architecture, we have reanalyzed the spatial organization of the initiation of mammalian DNA synthesis. Contrary to the commonly held view that replication begins at hundreds of dispersed nuclear sites, primary fibroblasts initiate synthesis in a limited number of...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Kennedy, Brian K., Barbie, David A., Classon, Marie, Dyson, Nicholas, Harlow, Ed
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2000
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317063/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11090133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.842600
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