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The Cyclin E/Cdk2 Substrate p220(NPAT) Is Required for S-Phase Entry, Histone Gene Expression, and Cajal Body Maintenance in Human Somatic Cells

Cyclin E/Cdk2, a central regulator of the G(1)/S transition, coordinates multiple cell cycle events, including DNA replication, centrosome duplication, and activation of the E2F transcriptional program. Recent studies suggest a role for cyclin E/Cdk2 in activation of histone transcription during S p...

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Detalhes bibliográficos
Main Authors: Ye, Xin, Wei, Yue, Nalepa, Grzegorz, Harper, J. Wade
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC262656/
https://ncbi.nlm.nih.gov/pubmed/14612403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8586-8600.2003
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