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The Cyclin E/Cdk2 Substrate p220(NPAT) Is Required for S-Phase Entry, Histone Gene Expression, and Cajal Body Maintenance in Human Somatic Cells
Cyclin E/Cdk2, a central regulator of the G(1)/S transition, coordinates multiple cell cycle events, including DNA replication, centrosome duplication, and activation of the E2F transcriptional program. Recent studies suggest a role for cyclin E/Cdk2 in activation of histone transcription during S p...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC262656/ https://ncbi.nlm.nih.gov/pubmed/14612403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8586-8600.2003 |
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