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The Cyclin E/Cdk2 Substrate and Cajal Body Component p220(NPAT) Activates Histone Transcription through a Novel LisH-Like Domain

p220(NPAT) is a substrate of cyclin E/Cdk2 that localizes in nuclear organelles called Cajal bodies in a cell cycle-regulated manner. In normal diploid fibroblasts, p220 is concentrated in two Cajal bodies tethered to histone gene clusters at chromosome 6p21 during G(1), S, and G(2) phases and two a...

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Detalhes bibliográficos
Main Authors: Wei, Yue, Jin, Jianping, Harper, J. Wade
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164767/
https://ncbi.nlm.nih.gov/pubmed/12724424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3669-3680.2003
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