The Cyclin E/Cdk2 Substrate and Cajal Body Component p220(NPAT) Activates Histone Transcription through a Novel LisH-Like Domain

p220(NPAT) is a substrate of cyclin E/Cdk2 that localizes in nuclear organelles called Cajal bodies in a cell cycle-regulated manner. In normal diploid fibroblasts, p220 is concentrated in two Cajal bodies tethered to histone gene clusters at chromosome 6p21 during G(1), S, and G(2) phases and two a...

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Опубликовано в::	Mol Cell Biol
Главные авторы:	Wei, Yue, Jin, Jianping, Harper, J. Wade
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 2003
Предметы:	Cell Growth and Development
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164767/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12724424/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.10.3669-3680.2003
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