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The Cyclin E/Cdk2 Substrate and Cajal Body Component p220(NPAT) Activates Histone Transcription through a Novel LisH-Like Domain
p220(NPAT) is a substrate of cyclin E/Cdk2 that localizes in nuclear organelles called Cajal bodies in a cell cycle-regulated manner. In normal diploid fibroblasts, p220 is concentrated in two Cajal bodies tethered to histone gene clusters at chromosome 6p21 during G(1), S, and G(2) phases and two a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164767/ https://ncbi.nlm.nih.gov/pubmed/12724424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3669-3680.2003 |
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