RANK is essential for osteoclast and lymph node development

The physiological role of the TNF receptor (TNFR) family member, RANK, was investigated by generating RANK-deficient mice. RANK(−/−) mice were characterized by profound osteopetrosis resulting from an apparent block in osteoclast differentiation. RANK expression was not required for the commitment,...

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Bibliografische Detailangaben
Veröffentlicht in:	Genes Dev
Hauptverfasser:	Dougall, William C., Glaccum, Moira, Charrier, Keith, Rohrbach, Kathy, Brasel, Kenneth, De Smedt, Thibaut, Daro, Elizabeth, Smith, Jeffery, Tometsko, Mark E., Maliszewski, Charles R., Armstrong, Allison, Shen, Victor, Bain, Steven, Cosman, David, Anderson, Dirk, Morrissey, Philip J., Peschon, Jacques J., Schuh, JoAnn
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 1999
Schlagworte:	Research Paper
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317030/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500098/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.18.2412
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RANK is essential for osteoclast and lymph node development

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