RANK is essential for osteoclast and lymph node development

The physiological role of the TNF receptor (TNFR) family member, RANK, was investigated by generating RANK-deficient mice. RANK(−/−) mice were characterized by profound osteopetrosis resulting from an apparent block in osteoclast differentiation. RANK expression was not required for the commitment,...

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Bibliografiske detaljer

Udgivet i:	Genes Dev
Principais autores:	Dougall, William C., Glaccum, Moira, Charrier, Keith, Rohrbach, Kathy, Brasel, Kenneth, De Smedt, Thibaut, Daro, Elizabeth, Smith, Jeffery, Tometsko, Mark E., Maliszewski, Charles R., Armstrong, Allison, Shen, Victor, Bain, Steven, Cosman, David, Anderson, Dirk, Morrissey, Philip J., Peschon, Jacques J., Schuh, JoAnn
Format:	Artigo
Sprog:	Inglês
Udgivet:	Cold Spring Harbor Laboratory Press 1999
Fag:	Research Paper
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317030/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500098/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.18.2412
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