Inhibition of RANK signaling as a potential immunotherapy in breast cancer
RANK signaling in mouse mammary tumor cells exerts an immunosuppressive environment by promoting the infiltration of pro-tumorigenic neutrophils and preventing CD8 T cell recruitment. Single-agent denosumab led to an increased tumor immune infiltration by lymphocytes and CD8 + T cells in breast canc...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis Group
2021-01-01
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| Edice: | OncoImmunology |
| Témata: | |
| On-line přístup: | http://dx.doi.org/10.1080/2162402X.2021.1923156 |
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