Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase

Studies have demonstrated that increased oxidative stress contributes to the pathogenesis and the development of pulmonary artery hypertension (PAH). Extracellular superoxide dismutase (SOD3) is essential for removing extracellular superoxide anions and it is highly expressed in lung tissue. However...

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Main Authors: Xu, Dachun, Guo, Haipeng, Xu, Xin, Lu, Zhongbing, Fassett, John, Hu, Xinli, Xu, Yawei, Tang, Qizhu, Hu, Dayi, Somani, Arif, Geurts, Aron, Ostertag, Eric, Bache, Robert J., Weir, E. Kenneth, Chen, Yingjie
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170043/
https://ncbi.nlm.nih.gov/pubmed/21730301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.166819
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