Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase

Studies have demonstrated that increased oxidative stress contributes to the pathogenesis and the development of pulmonary artery hypertension (PAH). Extracellular superoxide dismutase (SOD3) is essential for removing extracellular superoxide anions and it is highly expressed in lung tissue. However...

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Detalhes bibliográficos
Main Authors: Xu, Dachun, Guo, Haipeng, Xu, Xin, Lu, Zhongbing, Fassett, John, Hu, Xinli, Xu, Yawei, Tang, Qizhu, Hu, Dayi, Somani, Arif, Geurts, Aron, Ostertag, Eric, Bache, Robert J., Weir, E. Kenneth, Chen, Yingjie
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170043/
https://ncbi.nlm.nih.gov/pubmed/21730301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.166819
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