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Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase

Studies have demonstrated that increased oxidative stress contributes to the pathogenesis and the development of pulmonary artery hypertension (PAH). Extracellular superoxide dismutase (SOD3) is essential for removing extracellular superoxide anions and it is highly expressed in lung tissue. However...

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Autori principali: Xu, Dachun, Guo, Haipeng, Xu, Xin, Lu, Zhongbing, Fassett, John, Hu, Xinli, Xu, Yawei, Tang, Qizhu, Hu, Dayi, Somani, Arif, Geurts, Aron, Ostertag, Eric, Bache, Robert J., Weir, E. Kenneth, Chen, Yingjie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170043/
https://ncbi.nlm.nih.gov/pubmed/21730301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.166819
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