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Development of autoimmune diabetes in the absence of detectable interleukin-17A in a CD8-driven virally-induced model

Recent studies have shown that IL-17 can contribute beneficially to pathogen defense, but also that excessive IL-17 levels are associated with chronic inflammation and autoimmune disorders. So far, the role of IL-17 in viral infections and type 1 diabetes is ambiguous. In this study, we used IL-17A...

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Hlavní autoři: Van Belle, Tom L., Esplugues, Enric, Liao, Jeanette, Juntti, Therese, Flavell, Richard A., von Herrath, Matthias G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169711/
https://ncbi.nlm.nih.gov/pubmed/21832162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000180
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