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Pre-existing autoimmunity determines type 1 diabetes outcome after Flt3-ligand treatment

Redirection of immune responses by manipulation of antigen-presenting cells is an emerging strategy for immunosuppressive treatment of autoimmune diseases. In vivo expansion of dendritic cells (DC) by Fms-like tyrosine kinase-3 (Flt3)-Ligand (FL) treatment was shown to delay diabetes onset in the NO...

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Detalhes bibliográficos
Main Authors: Van Belle, Tom L., Juntti, Therese, Liao, Jeanette, von Herrath, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860005/
https://ncbi.nlm.nih.gov/pubmed/20004555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2009.11.010
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