Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression

The gut microbiota has been causally linked to cancer, yet how intestinal microbes influence progression of extramucosal tumors is poorly understood. Here we provide evidence implying that Prevotella heparinolytica promotes the differentiation of Th17 cells colonizing the gut and migrating to the bo...

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Vydáno v:Nat Commun
Hlavní autoři: Calcinotto, Arianna, Brevi, Arianna, Chesi, Marta, Ferrarese, Roberto, Garcia Perez, Laura, Grioni, Matteo, Kumar, Shaji, Garbitt, Victoria M., Sharik, Meaghen E., Henderson, Kimberly J., Tonon, Giovanni, Tomura, Michio, Miwa, Yoshihiro, Esplugues, Enric, Flavell, Richard A., Huber, Samuel, Canducci, Filippo, Rajkumar, Vincent S., Bergsagel, P. Leif, Bellone, Matteo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277390/
https://ncbi.nlm.nih.gov/pubmed/30510245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07305-8
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