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Prohibitin (PHB) acts as a potent survival factor against ceramide induced apoptosis in rat granulosa cells

AIM: Ceramide is a key factor in inducing germ cell apoptosis by translocating from cumulus cells into the adjacent oocyte and lipid rafts through gap junctions. Therefore studies designed to elucidate the mechanistic pathways in ceramide induced granulosa cell (GC) apoptosis and follicular atresia...

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Autors principals: Chowdhury, Indrajit, Branch, Alicia, Olatinwo, Moshood, Thomas, Kelwyn, Matthews, Roland, Thompson, Winston E.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169651/
https://ncbi.nlm.nih.gov/pubmed/21763324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2011.06.022
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