Prohibitin (PHB) acts as a potent survival factor against ceramide induced apoptosis in rat granulosa cells

AIM: Ceramide is a key factor in inducing germ cell apoptosis by translocating from cumulus cells into the adjacent oocyte and lipid rafts through gap junctions. Therefore studies designed to elucidate the mechanistic pathways in ceramide induced granulosa cell (GC) apoptosis and follicular atresia...

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Bibliografiske detaljer
Main Authors: Chowdhury, Indrajit, Branch, Alicia, Olatinwo, Moshood, Thomas, Kelwyn, Matthews, Roland, Thompson, Winston E.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169651/
https://ncbi.nlm.nih.gov/pubmed/21763324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2011.06.022
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