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Prohibitin (PHB) acts as a potent survival factor against ceramide induced apoptosis in rat granulosa cells

AIM: Ceramide is a key factor in inducing germ cell apoptosis by translocating from cumulus cells into the adjacent oocyte and lipid rafts through gap junctions. Therefore studies designed to elucidate the mechanistic pathways in ceramide induced granulosa cell (GC) apoptosis and follicular atresia...

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Detalhes bibliográficos
Main Authors: Chowdhury, Indrajit, Branch, Alicia, Olatinwo, Moshood, Thomas, Kelwyn, Matthews, Roland, Thompson, Winston E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169651/
https://ncbi.nlm.nih.gov/pubmed/21763324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2011.06.022
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