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Prohibitin (PHB) inhibits apoptosis in rat granulosa cells (GCs) through the extracellular signal-regulated kinase 1/2 (ERK1/2) and the Bcl family of proteins

Mammalian ovarian follicular development is tightly regulated by crosstalk between cell death and survival signals, which include both endocrine and intra-ovarian regulators. Whether the follicle ultimately ovulates or undergoes atresia is dependent on the expression and actions of factors promoting...

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Autori principali: Chowdhury, Indrajit, Thompson, Winston E., Welch, Crystal, Thomas, Kelwyn, Matthews, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825582/
https://ncbi.nlm.nih.gov/pubmed/24096434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-013-0901-z
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