The bHLH gene Hes1 is essential for expansion of early T cell precursors
Mice mutant for the bHLH gene Hes1, which is known to keep cells in a proliferative state, mostly lack thymus. Transfer of Hes1-null fetal liver cells into RAG2-null host mice normally reconstitutes B cells but fails to generate mature T cells in the thymus. In the reconstituted thymus, T cell diffe...
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| Publicado no: | Genes Dev |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316958/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10323870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.9.1203 |
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