The bHLH gene Hes1 is essential for expansion of early T cell precursors
Mice mutant for the bHLH gene Hes1, which is known to keep cells in a proliferative state, mostly lack thymus. Transfer of Hes1-null fetal liver cells into RAG2-null host mice normally reconstitutes B cells but fails to generate mature T cells in the thymus. In the reconstituted thymus, T cell diffe...
Sábháilte in:
| Foilsithe in: | Genes Dev |
|---|---|
| Príomhchruthaitheoirí: | , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
Cold Spring Harbor Laboratory Press
1999
|
| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316958/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10323870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.9.1203 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
|